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What Is Your Thyroid Gland?
Your thyroid gland is one of the endocrine glands, which make hormones to regulate physiological functions in your body. The thyroid gland manufactures thyroid hormone, which regulates the rate at which your body carries on its necessary functions. Other endocrine glands are the pancreas, the pituitary, the adrenal glands, the parathyroid glands, the testes, and the ovaries.

The thyroid gland is located in the middle of the lower neck, below the larynx (voice box) and just above your clavicles (collarbones). It is shaped like a "bow tie," having two halves (lobes): a right lobe and a left lobe joined by an "isthmus.". You can't always feel a normal thyroid gland.
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When Is A Thyroid Gland Abnormal?
Diseases of the thyroid gland are very common, affecting millions of Americans. The most common diseases are an over- or under-active gland. These conditions are called hyperthyroidism (e.g., Grave's disease) and hypothyroidism. Sometimes the thyroid gland can become enlarged from over-activity (as in Grave's disease) or from under-activity (as in hypothyroidism). An enlarged thyroid gland is often called a "goiter." Sometimes an inflammation of the thyroid gland (Hashimoto's disease) will cause enlargement of the gland.

Patients may develop "lumps" or "masses" in their thyroid glands. They may appear gradually or very rapidly. Patients who had radiation therapy to the head or neck as children for acne, adenoids, or other reasons are more prone to develop thyroid malignancy. A doctor should evaluate all thyroid "lumps" (nodules).



What Is Your Adrenal Gland?
The adrenal gland is really two glands in one. The adrenal cortex, the outer portion of the adrenal gland is responsible for the majority of the body's steroid production. The term corticosteroids is derived from this origin. Steroids have many functions but their main action is in form of salt retention which in turn leads to regulation of the blood pressure as well as sex steroid production.
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The adrenal medulla is the central portion of the gland and is primarily responsible for the production of catecholamines (epinephrine, norepinephrine, and dopamine).



Biopsies of the adrenal gland are uncommon but often performed to distinguish between a primary malignancy of the adrenal gland versus a metastasis, which is more common. Frequently, a CT guided fine needle aspiration is performed by the radiologist. The pathologist will take the aspiration specimen, smear it on a slide and stain it. Frequently, a diagnosis can be rendered sparing the patient a very invasive surgical procedure.
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The pancreas is a long, soft organ that lies transversely along the posterior abdominal wall, posterior to the stomach, and extends from the region of the duodenum to the spleen. This gland has an exocrine portion that secretes digestive enzymes that are carried through a duct to the duodenum. The endocrine portion consists of the pancreatic islets, which secrete glucagons and insulin.



Alpha cells in the pancreatic islets secrete the hormone glucagons in response to a low concentration of glucose in the blood. Beta cells in the pancreatic islets secrete the hormone insulin in response to a high concentration of glucose in the blood.

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Pituitary Gland - Secretes hormones to stimulate the adrenals, thyroid, pigment-producing skin cells and gonads (ovaries and testes). Also secretes a growth hormone, an antidiuretic hormone, prolactin (a hormone which affects milk production after childbirth) and oxytocin (a hormone which plays a role in childbirth).

Hypothalamus - Secretes hormones that stimulate or suppress the release of hormones in the pituitary gland.






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